The triple combination therapy of ezetimibe/simvastatin plus niacin safely reduces cholesterol better
than ezetimibe/simvastatin alone, according to a study in the Feb. 15 American Journal of Cardiology.
In patients with spinal stenosis, those without concomitant degenerative spondylolisthesis or
scoliosis can be managed nonoperatively regardless of the number of levels; and, if surgery is performed, the
number of levels treated does not predict outcome. However, among patients with concomitant degenerative
spondylolisthesis, those with only single level stenosis tend to improve more than those with multilevel stenosis,
especially after surgery, according to a research published in the Feb. 15 issue of Spine.
The use of chiropractic spinal manipulation for the neck and upper thoracic spine may be useful in
treating cervicogenic headache, according to research published in the February issue of The Spine
Journal.
A risk score that includes patient information available at discharge can identify the risk of
mortality in individuals hospitalized with advanced decompensated heart failure, according to research published in
the March 2 issue of the Journal of the American College of Cardiology.
In patients with ST-segment elevation myocardial infarction, the use of routine distal protection is
associated with a higher rate of adverse cardiac events, according to research published in the March 2 issue of
the Journal of the American College of Cardiology.
Prophylactic removal of the opposite breast has a slight survival benefit in younger women with
early-stage estrogen receptor-negative breast cancer, according to a study published online Feb. 25 in the Journal
of the National Cancer Institute.
Personalized tumor-specific biomarkers based on the chromosomal rearrangements present in an
individual patient can be detected with high sensitivity in blood and used to monitor the efficacy of treatment in
cancer patients, according to a study in the Feb. 24 issue of Science Translational Medicine.
The general prognosis in patients with peripheral arterial disease is worse in those with proximal
disease than those with more distal disease, according to research published in the March 2 issue of the Journal of
the American College of Cardiology.
Men with prostate cancer have similar postoperative complications and need for additional treatment
regardless of whether they undergo radical prostatectomy by an open or laparoscopic procedure, according to a study
published online Feb. 25 in The Journal of Urology.
Patients undergoing foot and ankle surgery are more likely to have postoperative infections if they
have complicated diabetes mellitus, while patients with uncomplicated diabetes do not appear to have a higher risk
than patients without diabetes, according to research published in the Feb. 1 issue of the Journal of Bone
& Joint Surgery.
Obese and overweight patients who undergo percutaneous coronary intervention to receive drug-eluting
stents, are at higher risk of adverse outcomes by one-year follow-up than normal weight patients, according to a
study in the Feb. 15 issue of the American Journal of Cardiology.
A behavioral intervention that encourages physical activity in patients with chronic lower back pain
reduces disability and pain and is cost-effective, according to a study published online Feb. 26 in The
Lancet.
Intermittently blocking blood flow in the arm, known as remote conditioning, during the ambulance ride
to the hospital (before stenting) reduces damage to the heart after a heart attack, possibly by activating
protective mechanisms in the heart, according to a study in the Feb. 27 issue of The Lancet.
Coffee consumption may be associated with a lower risk of stroke, according to research presented at
the American Stroke Association's 2010 International Stroke Conference, held from Feb. 23 to 26 in San
Antonio.
Carotid stenting and carotid endarterectomy have similar long-term outcomes for preventing stroke in
patients with carotid stenosis, according to a study presented at the American Stroke Association's 2010
International Stroke Conference, held from Feb. 23 to 26 in San Antonio. However, two studies published online Feb.
26 in The Lancet and The Lancet Neurology found that carotid stenting is associated with worse outcomes than
carotid endarterectomy in patients with carotid artery stenosis in the months after the procedure and is associated
with ischemic brain lesions shortly after treatment.
Vitamin D receptor agonists can reduce the growth of prostate cancer cells containing a common,
androgen-regulated, growth-promoting gene fusion, according to a study published online Feb. 10 in
Endocrinology.
Eradication of Helicobacter pylori in the stomachs of patients with early-stage gastric lymphoma
results in the remission of approximately 75 percent of them, according to a meta-analysis reported in the February
issue of Clinical Gastroenterology and Hepatology.
Certain foods are associated with an increased or a decreased risk of bladder cancer, and diet should
be a component of care for patients with the disease, according to an article published in the February issue of
Urology.
New drugs that block the replication of the hepatitis C virus are likely to lead to resistance if
given as monotherapy and should be given in combination with pegylated interferon and ribavirin, according to a
review in the February issue of Gastroenterology.
In the prediction of curve flexibility and postoperative correction in adolescent idiopathic
scoliosis, traction under general anesthesia radiographs perform equivalently to supine bending radiographs,
according to a study in the Feb. 15 issue of Spine.
In an effort to remove barriers to seasonal influenza vaccination, the Advisory Committee on
Immunization Practices, which advises the U.S. Centers for Disease Control and Prevention, has voted to expand the
annual influenza vaccination recommendation to include all individuals 6 months and older, taking effect during the
2010/2011 influenza season.
A large proportion of young adults in the United States are without health insurance, and men in this
age group are more likely to be uninsured than women, according to a new report issued Feb. 24 by the National
Center for Health Statistics.
Women who give birth over the age of 40 are more likely than their younger counterparts to have a
child with autism, but the father's age only affects the odds of autism when the mother is under 30, according to a
study published online Feb. 8 in Autism Research.
A model that takes changes in risk factors over time into account can predict who is at high risk of
developing prostate cancer among men whose biopsies are initially negative, according to a study published online
Feb. 22 in the Journal of Clinical Oncology.
Mice lacking a dopamine receptor have an impaired insulin response and glucose intolerance, which may
explain why certain neuroleptic drugs that block this receptor cause hyperinsulinemia or diabetes, according to a
study published online Feb. 10 in Endocrinology.
The complexity, fast pace and unpredictability of the perioperative environment make critical thinking
skills crucial for perioperative nurses, and although such skills are taught as part of nursing training, they can
only be honed by practical experience, according to a review of critical thinking in the nursing context published
in the February issue of the AORN Journal.
In endometrial cancer patients at high risk of recurrence, combined pelvic and para-aortic
lymphadenectomy reduces the risk of recurrence significantly better than systemic pelvic lymphadenectomy, according
to a study published online Feb. 25 in The Lancet.
About 70 percent of vascular disease patients take aspirin, mainly for secondary prevention. While
some non-aspirin users take other antithrombotic agents, almost 15 percent of patients take no antithrombotic agent
at all, according to research published in the Feb. 15 American Journal of Cardiology.
Annual colonoscopies can provide timely detection of early-stage colorectal cancer in the high-risk
group of people with the genetic condition known as hereditary nonpolyposis colorectal cancer, according to a study
in the February issue of Clinical Gastroenterology and Hepatology.
Strokes may be striking more people at younger ages, according to research presented at the American
Stroke Association's 2010 International Stroke Conference, held from Feb. 23 to 26 in San Antonio.
In adult kidney transplant patients, belatacept -- a selective costimulation blocker -- is associated
with better renal function and similar patient/graft survival at one year compared to cyclosporine, with these
benefits also seen in recipients of extended criteria donor kidneys, according to two studies published online Feb.
16 in the American Journal of Transplantation.
In patients with HIV and tuberculosis, starting antiretroviral therapy during tuberculosis treatment
is associated with better survival; and, in people with HIV, screening for tuberculosis should include questions
about symptoms other than just chronic cough, according to the results of two studies in the Feb. 25 New England
Journal of Medicine.
The nonsteroidal selective estrogen-receptor modulator lasofoxifene may reduce the risk of fractures,
stroke, estrogen receptor-positive breast cancer, and coronary heart disease in postmenopausal women with
osteoporosis. However, the drug significantly increases the risk of venous thromboembolic events, according to a
study in the Feb. 25 issue of the New England Journal of Medicine.
The vaginal ring has a similar level of acceptability to young women as the oral contraceptive pill,
but neither method appears to be particularly popular for long-term use in this population, according to a study in
the March issue of Obstetrics & Gynecology.
A school-based intervention that incorporates compulsory exercise sessions as well as physical
education homework helps children become more active and fit and reduces adiposity, according to a study published
Feb. 23 in BMJ.
In patients with (sub) acute low back pain, the Acute Low Back Pain Screening Questionnaire Dutch
Language Version may help identify those at risk of developing chronic low back pain because of psychosocial
factors, according to a study in the Feb. 15 issue of Spine.
Nephron-sparing surgery confers the same degree of cancer control as radical nephrectomy when treating
T1bN0M0 renal cell carcinoma, according to a study in the February issue of Urology.
Iron supplementation for anemia after hip fracture surgery does not significantly improve hemoglobin
levels, bringing into question the current practice of iron supplementation after orthopedic surgery, according to
a study in the Feb. 1 issue of the Journal of Bone & Joint Surgery.
Women who have a test for the human papillomavirus after receiving a borderline abnormal cervical
smear result have better psychosocial outcomes over the long term than women who have a repeat smear test,
according to a study published Feb. 23 in BMJ.
Two biomarkers are less effective than ultrasound in detecting early liver cancer in high-risk
patients with advanced hepatitis C, according to a study in the February issue of Gastroenterology.
The use of full-body scanners as part of airport security carries a negligible health risk due to
radiation, but there are still valid concerns about invasion of privacy, according to an editorial published Feb.
23 in BMJ.
In transient ischemic attack patients with brain infarction, a prognostic tool can identify those at
risk of a subsequent stroke. In addition, smokers tend to present with TIA at an earlier age than nonsmokers, and a
post-TIA rehabilitation program may improve cardiac and physical function, according to research presented at the
American Stroke Association's 2010 International Stroke Conference, held from Feb. 23 to 26 in San
Antonio.
A recent report from the American Stroke Association, published online Feb. 24 in Stroke, outlines
their efforts over the last 10 years to reduce death and disability associated with stroke, and suggests that
current practice should focus more on prevention and recovery than previously recommended. The report was released
to coincide with the ASA's 2010 International Stroke Conference, held from Feb. 23 to 26 in San
Antonio.
Stroke care and patient outcomes have improved significantly for hospitals participating in the
American Heart Association/American Stroke Association's Get With The Guidelines-Stroke program, according to an
analysis presented at the American Stroke Association's 2010 International Stroke Conference, held from Feb. 23 to
26 in San Antonio, and published online Feb. 22 in Circulation: Cardiovascular Quality and Outcomes.
In patients with an unwitnessed ischemic stroke, treatment with recombinant tissue-plasminogen
activator should be considered for those who were "last seen normal" within several hours of the
stroke, according to research presented at the American Stroke Association's 2010 International Stroke Conference,
held from Feb. 23 to 26 in San Antonio.
Resuscitation to normalize lactate clearance in patients suffering from septic shock resulted in
in-hospital mortality similar to that for patients resuscitated to normalize central venous oxygen saturation,
according to a study in the Feb. 24 issue of the Journal of the American Medical Association.
Patients undergoing spine surgery do not have a significant risk of deep venous thrombosis or
pulmonary embolism, particularly if they are given pharmacologic prophylaxis, but this measure raises the risk of
epidural hematoma, according to research published in the Feb. 1 issue of the Journal of Bone & Joint
Surgery.
When primary care physicians need to deny patient requests for tests and treatments, strategies that
incorporate the patient perspective may be most effective, according to a study in the Feb. 22 issue of the
Archives of Internal Medicine.
Completing clerical documentation eats up valuable time and too often does not generate any meaningful
feedback for internal medicine residents, according to a study in the Feb. 22 issue of the Archives of Internal
Medicine.
Although quinine derivatives appear effective for muscle cramps, these agents should be avoided for
routine treatment of muscle cramps due to the possibility of serious side effects, according to an article
published in the Feb. 23 issue of Neurology.
Three tests of platelet function can modestly predict outcomes such as death and stroke in patients
taking clopidogrel (Plavix) and undergoing elective coronary stent implantation, but they do not identify patients
at higher risk of bleeding, according to a study in the Feb. 24 issue of the Journal of the American Medical
Association.
Physicians in the United States have been working fewer hours for lower fees in the past decade,
according to research published in the Feb. 24 issue of the Journal of the American Medical
Association.
Novartis Oncology has alerted health care professionals about changes in the prescribing information
for deferasirox (Exjade), a treatment for chronic iron overload due to blood transfusions in patients 2 years of
age and older, according to a Feb. 18 safety alert issued by the U.S. Food and Drug Administration.
A minimally invasive approach for hip replacement has no advantage over the standard approach with
regard to gait kinematics, according to a study in the Feb. 1 Journal of Bone & Joint Surgery. A
related review in the same issue suggests that racial and ethnic minorities may have a higher risk of death or
complications after knee or hip replacement.
New strategies are needed to combat hypertension, which affects nearly one-third of U.S. adults and
accounts for about one in six adult deaths each year, according to the new report, A Population-Based Policy and
Systems Change Approach to Prevent and Control Hypertension, released Feb. 22 by the Institute of
Medicine.
Multi-disciplinary teams conducting daily rounds may lower the risk of mortality among medical
patients in intensive care units, according to a study in the Feb. 22 issue of the Archives of Internal Medicine,
while another study found that there is a growing need for internal medicine education to include training in the
medical management of surgical patients, in line with the growing trend of comanagement of hospitalized
patients.
Hospital-acquired sepsis and pneumonia impose a significant financial and clinical burden, according
to a study published in the Feb. 22 issue of the Archives of Internal Medicine, while another study found that
hospitals that keep costs down do not necessarily have poorer quality of care or higher readmission
rates.
The U.S. Food and Drug Administration has alerted health care professionals and consumers that the HIV
drug combination of saquinavir (Invirase) and ritonavir (Norvir) may increase the risk of potentially serious
cardiac arrhythmias in a dose-dependent manner.This is an early communication from the FDA with ongoing review of
the data.
The U.S. Food and Drug Administration has informed health care professionals that the organization is
currently reviewing cardiovascular safety data associated with rosiglitazone (Avandia), a type 2 diabetes drug,
from the Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycemia in Diabetes study as well
as from other recently published safety analyses.
In physically inactive patients with chronic conditions, exercise training may significantly reduce
anxiety, according to a systematic review published in the Feb. 22 issue of the Archives of Internal
Medicine.
Elderly adults who are hospitalized for an acute or critical illness are more likely to experience
cognitive decline, and the risk of developing dementia is significantly higher after hospitalization for a
non-critical illness, according to research published in the Feb. 24 issue of the Journal of the American Medical
Association.
Despite some gains in public awareness, almost half of all American women are unaware that heart
disease is the leading cause of death in women, according to research published online Feb. 10 in Circulation:
Cardiovascular Quality and Outcomes.
The elevation of total urinary protease and several urinary proteins may offer novel biomarkers in the
diagnosis of lupus nephritis, according to a mouse study in the Feb. 15 issue of the Journal of
Immunology.
Serum cell-free DNA integrity may serve as a predictive marker for the diagnosis and detection of
clear renal cell carcinoma, according to a study in the February issue of Urology.
Regulatory agencies, pediatricians, parents and caregivers, toy manufacturers, and food companies
should take concrete steps to reduce the risk of choking in young children, according to a policy statement from
the American Academy of Pediatrics published online Feb. 22 in Pediatrics.
There are significant differences between chronic and episodic migraine sufferers in terms of
sociodemographic factors and comorbidities, according to research published online Feb. 17 in the Journal of
Neurology, Neurosurgery & Psychiatry.
The checklists so common in aviation and many professions are underused in medicine and, if more
widely adopted, would provide powerful tools to standardize care and improve patient outcomes, according to an
article published Dec. 31 in Critical Care.
Exposure to antidepressants in late pregnancy may affect children's developmental milestones,
according to a study published online Feb. 22 in Pediatrics.
The vascular endothelial growth factor inhibitor bevacizumab administered by intranasal injection, or
even by topical nasal spray, can effectively treat epistaxis from hereditary hemorrhagic telangiectasia, according
to reports published in The Laryngoscope.
A midday nap may significantly improve the brain's learning capacity, a process that may be associated
with stage 2 non-REM sleep, according to research presented this week at the annual meeting of the American
Association for the Advancement of Science, held from Feb. 18 to 22 in San Diego.
Obese children who undergo cardiopulmonary resuscitation in the hospital are at greater risk of dying
before hospital discharge than normal weight or underweight children, according to a study published online Feb. 22
in Pediatrics.
Acetylation has an important role in the regulation of metabolism, with nearly all enzymes involved in
a variety of processes in the human liver found to be acetylated, according to research published in the Feb. 19
issue of Science. The researchers state these findings provide novel clues on how normal cells function and may
lead to information on why normal cells turn cancerous.
many of us in the interdisciplinary field of medical humanities believe that it is only through a meeting of the minds between biomedicine and other fields such as literature, art, philosophy and history that we can understand the experiences of patients and providers of care (roles that almost all of us will inhabit at some point in our lives). 
: skip to main skip to sidebar Crusades-Medieval crusades timeline , crusades history , crusades in the middle ages , crusades map , crusades lesson plans , crusades definition , crusades holy land , medieval times , medieval names , medieval weapons , medieval clothing , medieval times coupons , medieval castles , medieval torture , medieval costumes , middle ages timeline , middle ages clothing , middle ages art , middle ages food , middle ages brewery , middle ages weapons , middle ages castles , middle ages knights , middle ages medieval The Middle Ages or the medieval age is a period of European history covering around a millennium from the fifth century through to the sixteenth century . It is commonly dated from the drop of the Western Roman Empire , and counterpointed with a later Early Modern Period the time during which the grow of humanism in the Italian Renaissance and the Reformation extended , are generally associated with the transition out of the Middle Ages , with European overseas expansion as a succeeding process , but such dates are approximate and based upon nuanced statements . Medieval society was assorted , but not so different as to be completely alien to: skip to main skip to sidebar Crusades-Medieval crusades timeline , crusades history , crusades in the middle ages , crusades map , crusades lesson plans , crusades definition , crusades holy land , medieval times , medieval names , medieval weapons , medieval clothing , medieval times coupons , medieval castles , medieval torture , medieval costumes , middle ages timeline , middle ages clothing , middle ages art , middle ages food , middle ages brewery , middle ages weapons , middle ages castles , middle ages knights , middle ages medieval The Middle Ages or the medieval age is a period of European history covering around a millennium from the fifth century through to the sixteenth century . It is commonly dated from the drop of the Western Roman Empire , and counterpointed with a later Early Modern Period the time during which the grow of humanism in the Italian Renaissance and the Reformation extended , are generally associated with the transition out of the Middle Ages , with European overseas expansion as a succeeding process , but such dates are approximate and based upon nuanced statements . Medieval society was assorted , but not so different as to be completely alien to: skip to main skip to sidebar Crusades-Medieval crusades timeline , crusades history , crusades in the middle ages , crusades map , crusades lesson plans , crusades definition , crusades holy land , medieval times , medieval names , medieval weapons , medieval clothing , medieval times coupons , medieval castles , medieval torture , medieval costumes , middle ages timeline , middle ages clothing , middle ages art , middle ages food , middle ages brewery , middle ages weapons , middle ages castles , middle ages knights , middle ages medieval The Middle Ages or the medieval age is a period of European history covering around a millennium from the fifth century through to the sixteenth century . It is commonly dated from the drop of the Western Roman Empire , and counterpointed with a later Early Modern Period the time during which the grow of humanism in the Italian Renaissance and the Reformation extended , are generally associated with the transition out of the Middle Ages , with European overseas expansion as a succeeding process , but such dates are approximate and based upon nuanced statements . Medieval society was assorted , but not so different as to be completely alien to: skip to main skip to sidebar Crusades-Medieval crusades timeline , crusades history , crusades in the middle ages , crusades map , crusades lesson plans , crusades definition , crusades holy land , medieval times , medieval names , medieval weapons , medieval clothing , medieval times coupons , medieval castles , medieval torture , medieval costumes , middle ages timeline , middle ages clothing , middle ages art , middle ages food , middle ages brewery , middle ages weapons , middle ages castles , middle ages knights , middle ages medieval The Middle Ages or the medieval age is a period of European history covering around a millennium from the fifth century through to the sixteenth century . It is commonly dated from the drop of the Western Roman Empire , and counterpointed with a later Early Modern Period the time during which the grow of humanism in the Italian Renaissance and the Reformation extended , are generally associated with the transition out of the Middle Ages , with European overseas expansion as a succeeding process , but such dates are approximate and based upon nuanced statements . Medieval society was assorted , but not so different as to be completely alien to: skip to main skip to sidebar Crusades-Medieval crusades timeline , crusades history , crusades in the middle ages , crusades map , crusades lesson plans , crusades definition , crusades holy land , medieval times , medieval names , medieval weapons , medieval clothing , medieval times coupons , medieval castles , medieval torture , medieval costumes , middle ages timeline , middle ages clothing , middle ages art , middle ages food , middle ages brewery , middle ages weapons , middle ages castles , middle ages knights , middle ages medieval The Middle Ages or the medieval age is a period of European history covering around a millennium from the fifth century through to the sixteenth century . It is commonly dated from the drop of the Western Roman Empire , and counterpointed with a later Early Modern Period the time during which the grow of humanism in the Italian Renaissance and the Reformation extended , are generally associated with the transition out of the Middle Ages , with European overseas expansion as a succeeding process , but such dates are approximate and based upon nuanced statements . Medieval society was assorted , but not so different as to be completely alien to